期刊论文

Research Progress on Animal Model Construction and Model Evaluation of Spleen Yang Deficiency Syndrome

中文

中医药导报

1672-951X

2019

25

16

116-119

10.13862/j.cnki.cn43-1446/r.2019.16.030

81703920:国家自然科学基金 201780:湖南省中医药局一般项目 2017280:湖南省大学生研究性学习和创新性实验计划

本校为第一机构

从中医单因素造模法、西医单因素造模法、中医复合因素造模法、中西医结合复合因素造模法概述了中医学脾阳虚证候的造模方法;从宏观评价指标、形态学指标、功能性指标、细胞分子指标综述了脾阳虚证候模型成功构建的评价方法;尽管脾阳虚证动物模型的建立现已取得一定成果,但仍存在一些问题尚待解决。选择更加贴合临床实践的脾阳虚证候模型,建立更加标准、更具特异性的模型评价体系仍是中医脾胃藏象学说未来研究的方向。

This article mainly summarizes the methods of modeling Spleen-Yang deficiency syndrome in traditional Chinese medicine from the single-factor method of traditional Chinese medicine,the single-factor method of Western medicine,the compound factor method of traditional Chinese medicine,and the combined factor method of traditional Chinese and Western medicine.In addition,the evaluation methods of successful construction of Spleen-Yang deficiency syndrome model were summarized from macro-evaluation index,morphological index,functional index,and cell and molecular indexes.Although the establishmen...