Objective To probe an effective method for treatment of poststroke limb spasticity and effects on glutamic acid (Glu) and aminobutyric acid (GABA) contents in spinal fluid (CSF). Methods One hundred and twelve cases were randomly divided into treatment group and control group,56 cases in each group. The treatment group were treated by muscle-tendon needling method and the control group by Yangming needling method. Glu and GABA contents in CSF before and after treatment were determined by high performance liquid chromatography. Results According to rehabilitation medicine assessment and Glu and...