期刊论文

Effects of ligustrazine(川芎嗪) on expression of vascular endothelial growth factor(VEGF) and VEGF mRNA after focal cerebral ischemia in rats

中文

中国中西医结合急救杂志

1008-9691

2008

15

6

329-331

10.3321/j.issn:1008-9691.2008.06.003

湖南省自然科学基金资助项目(08JJ4008) 湖南省教育厅科研基金重点项目(07A050) 湖南省教育厅科研基金青年项目(06B068) 湖南省科技厅社会发展科研基金资助项目(04SK3054) 湖南省卫生厅科技基金资助项目(B2006-133)

本校为第一机构

Objective To observe the effects of ligustrazine(川芎嗪) on vascular endothelial growth factor(VEGF) in rats with focal cerebral ischemia.Methods Fifteen Sprague-Dawley(SD) rats were randomly divided into three groups namely: sham operation group,model group, and ligustrazine group.Focal cerebral infarction model was established by sodium laurate which may induce vascular endothelial cell injury.Some indexes were detected such as VEGF mRNA expression examin...