Qiwei Baizhu San was found to have an inhibitory effect on human rotavirus at monolayers of MA104 cells. A 50% reduction in plaque number, a 101.86 TCID50 decrease in viral replication index and an around 60% inhibition in viral RNA synthesis were observed at concentration of 100 mg/ml. Furthermore, the cytotoxicity of the decoction was low, while its promoting effect on growth and proliferation of the culture cells was observed at the concentrations of 12.5~50 mg/ml. The decoction was also found to have effects in prolonging the survival time of infected cell...
