期刊论文

Wang, Y.J.

中文

中国中西医结合杂志

1003-5370

2005

25

5

412-415

10.3321/j.issn:1003-5370.2005.05.007

湖南省中医管理局资助课题（No.202021）；

本校为第一机构

目的观察清肝降糖片对多代谢综合征(MMS)胰岛素抵抗(IR)的影响.方法采用随机对照双盲法,将60例符合中西医诊断标准的MMS患者分为二甲双胍组及清肝降糖片组,每组30例,清肝降糖片组口服清肝降糖片,每次3片,每日2次;二甲双胍组口服二甲双胍每次3片(含0.425g),每日2次.两组均以1个月为1个疗程,连续观察2个疗程.结果两组均能显著降低血糖;两组治疗后空腹及餐后胰岛素、C肽水平均较治疗前明显下降;IR降低;β细胞功能明显改善;两组比较差异无显著性.两组治疗前后血浆游离脂肪酸水平比较差异无显著性.结论清肝降糖片具有降糖、降脂、降压及减轻胰岛素抵抗,改善β细胞功能的功效.

OBJECTIVE: To observe the effect of Qinggan Jiangtang tablet (QJT) in improving the insulin resistance (IR) in patients with multiple metabolic syndrome (MMS). METHODS: Adopting randomized controlled double-blinded method, 60 patients with MMS were divided equally into two groups. The treated group was treated by oral taking of QJT 3 tabs, twice a day and the control group treated by oral taking of Glucophage 3 tabs, twice a day, the therapeutic course for both groups was 1 month, and the observation lasted for 2 successive courses. RESULTS: After treatment, levels of blood glucose, fasting an...