Sini Powder Alleviates Stress Response and Suppresses Hepatocellular Carcinoma Development by Restoring Gut Microbiota

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Mei, Si;Deng, Zhe;Meng, Fan-ying;Guo, Qian-qian;Tao, He-yun;...

通讯作者：

Tian, XF

作者机构：

[Mei, Si] Hunan Univ Chinese Med, Fac Med, Changsha 410208, Peoples R China.

[Tao, He-yun; Tian, XF; Guo, Qian-qian; Tian, Xue-fei; Deng, Zhe; Meng, Fan-ying; Zhang, Lin] Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Peoples R China.

[Xi, Chang] Hunan Univ Chinese Med, Sch Humanities & Management, Changsha 410208, Peoples R China.

[Zhou, Qing] Hunan Univ Chinese Med, Clin Coll Tradit Chinese Med 1, Changsha 410007, Peoples R China.

[Tian, XF; Tian, Xue-fei] Hunan Univ Chinese Med, Fac Int Educ, Changsha 410208, Peoples R China.

通讯机构：

[Tian, XF ] H

Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Peoples R China.

Hunan Univ Chinese Med, Fac Int Educ, Changsha 410208, Peoples R China.

语种：

英文

关键词：

Sini Powder;Chinese medicine;hepatocellular carcinoma;gut microbiota;beta-adrenergic receptors-2;stress

期刊：

中国结合医学杂志

ISSN：

1672-0415

年：

2025

页码：

1-10

DOI：

10.1007/s11655-025-4127-z

基金类别：

Natural Science Foundation of Hunan Province [2023JJ40481]; Education Department of Hunan Province [21B0374]; Hunan University of Chinese Medicine [2024XJZA001]

机构署名：

本校为第一且通讯机构

院系归属：

中西医结合学院

摘要：

OBJECTIVES: To explore the underlying pharmacological mechanisms and its potential effects of Chinese medicine herbal formula Sini Powder (SNP) on hepatocellular carcinoma (HCC). METHODS: The active components of SNP and their in vivo distribution were identified using ultraperformance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Construction of component-target-disease networks, protein-protein interaction network, Gene Ontology function and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis,...

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Sini Powder Alleviates Stress Response and Suppresses Hepatocellular Carcinoma Development by Restoring Gut Microbiota

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