期刊论文

Dosimetric Study of Intensity Modulated Radiation Therapy and Body Gamma-Knife Radiosurgery for Peripheral Non-small-cell Lung Cancer

中文

医学临床研究

1671-7171

2018

35

6

1041-1043,1046

10.3969/j.issn.1671-7171.2018.06.001

湖南省教育厅资助项目（课题号：17C0966）

本校为其他机构

[目的]比较体部伽马刀和调强适形放射治疗(IMRT)技术对周围型非小细胞肺癌(NSCLC)实施放疗计划的剂量学特点.[方法]对11例NSCLC同时应用体部伽马刀和IMRT制定放射治疗计划,总剂量为66 Gy.计划标准为处方剂量至少覆盖95％的计划靶体积(PTV),各危及器官剂量均要求在耐受剂量范围内.通过靶区的等剂量分布、剂量体积直方图(DVH)以及适形指数(CI)和均匀指数(HI)等比较肿瘤靶区剂量和正常组织受照射剂量的差异.[结果]IMRT计划的CI和HI均优于伽马刀计划;伽马刀计划周围正常组织的剂量全肺的V5、V10、V20、V30均显著低于IMRT计划(P

[Objective]To investigate the dosimetric characteristic of radiotherapy for peripheral non-small-cell lung cancer （NSCLC） with body y-knife （MASEP body 7-knife） and intensity modulated radiation therapy （IMRT）.[Meth- ods]A total of 11 patients with peripheral non-small-cell lung cancer were selected in the study. Two treatment plans were designed for each patient, including γ-knife and IMRT. The total prescribed dose was 66 Gy for each patient. The plan- ning standard was that the prescribed dose covered at least 95 % of the planned targ...