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Autophagy in cerebral ischemia and the effects of traditional Chinese medicine

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Link by 中国知网学术期刊
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成果类型:
期刊论文
作者:
Xiao-ping Huang;Huang Ding;Jin-dong Lu;Ying-hong Tang;Bing-xiang Deng;...
作者机构:
[Chang-qing Deng; Xiao-ping Huang] Molecular Pathology Laboratory, Hunan University of Chinese Medicine, Changsha 410208, Hunan Province, China
[Huang Ding; Ying-hong Tang] Key Laboratory of Hunan Province for Prevention and Treatment of Integrated Traditional Chinese and Western Medicine on Cardio-cerebral Diseases, Changsha 410208, Hunan Province, China
[Bing-xiang Deng; Jin-dong Lu] Key Laboratory of Hunan Universities for Cell Biology and Molecular Techniques, Changsha 410208, Hunan Province, China
[Chang-qing Deng] E-mail: dchangq@sohu.com
语种:
英文
关键词:
autophagy;brain ischemia;drugs, Chinese herbal;medicine, traditional Chinese;review
关键词(中文):
脑缺血;自噬;中药;神经退行性疾病;心脑血管疾病;细胞成分;肿瘤细胞;活性物质
期刊:
结合医学学报:英文版
ISSN:
2095-4964
年:
2015
卷:
13
期:
5
页码:
289-296
基金类别:
supported by the National Natural Science Foundation of China (No. 81102557) the Aid Project for Innovation Platform Open Fund of Hunan Province University (No. 14K068) the Key Project of Administration of Traditional Chinese Medicine of Hunan Province (No. 201301, No. 201508) General Project of Science and Technology Department of Hunan Province (No. 2014SK3001) the Ministry of Education Key Laboratory Open Fund Established by the Province and the Ministry (No. ZYNK201405) the Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province the Hunan Province Natural Science Innovation Group
机构署名:
本校为第一机构
院系归属:
中西医结合学院
摘要:
Autophagy is a lysosome-mediated degradation process for non-essential or damaged cellular constituents, playing an important homeostatic role in cell survival, differentiation and development to maintain homeostasis. Autophagy is involved in tumors as well as neurodegenerative, cardiovascular and cerebrovascular diseases. Recently, active compounds from traditional Chinese medicine (TCM) have been found to modulate the levels of autophagy in tumor cells, nerve cells, myocardial cells and endothelial cells. Ischemic stroke is a major cause of neurological disability and places a heavy burden o...

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