National Natural Science Foundation of China [81774129]; Provincial Natural Science Foundation of Hunan [2019JJ50441, 2018JJ2296]; Hunan Science and Technology Plan Program [2019RS1064]; Provincial Education Department Science Foundation of Hunan [18B246, 19K065]; Hunan Administration of Traditional Chinese Medicine Science Foundation [201825]; Hunan Provincial "domestic first-class cultivation discipline - Integrated Chinese and western medicine discipline" Science Foundation [2019ZXYJHO6]; Academy of Finland (AKA) [201825] Funding Source: Academy of Finland (AKA)
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摘要：
Alzheimer's disease (AD) is an age-related neurodegenerative disease with a high incidence worldwide, and with no medications currently able to prevent the progression of AD. Danggui-Shaoyao-San (DSS) is widely used in traditional Chinese medicine (TCM) and has been proven to be effective for memory and cognitive dysfunction, yet its precise mechanism remains to be delineated. The present study was designed to investigate the genome-wide expression profile of long non-coding RNAs (LncRNAs) and messenger RNAs (mRNAs) in the hippocampus of APP/PS...
