National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30870915]; Hunan Provincial Innovation Foundation [CX2010B096]; Central South University Open Sharing Foundation [Zkj2009013]
机构署名：
本校为其他机构
院系归属：
医学院
摘要：
Vasoactive intestinal peptide (VIP) is one of the most plentiful neuropeptides in the lung and it has anti-inflammatory effects in the respiratory system. Triggering receptors expressed on myeloid cells-1 (TREM-1) and triggering receptors expressed on myeloid cells-2 (TREM-2) regulate immune responses to lipopolysaccharide (LPS). In the present study, we tested the expressions of TREM-1 and TREM-2 in various pulmonary cell lines and/or tissue using an animal model of LPS-induced acute lung injury (ALI), and determined the effects of VIP on expression of the TREM-1 and TREM-2 in lung tissues an...
