期刊论文

The Dynamic Changes of Nerve Growth factor （NGF） Immunohistochemical Expression in Spinal Cord Injury with Incomplete Paraplegia Rabbit

中文

航空航天医学杂志

2095-1434

2010

21

1

7-9

10.3969/j.issn.2095-1434.2010.01.004

基金项目：国家自然科学基金资助项目（399709260）

本校为第一机构

目的:探讨兔不完全性截瘫后损伤脊髓神经生长因子(NGF)阳性表达的动态变化,探讨NGF在脊髓损伤过程中的作用。方法:采用压迫法造成不完全截瘫兔模型,于伤后6 h、7、15 d取损伤脊髓组织3.0 mm长,用免疫组织化学S-P法染色,并用美国产Optim as6.51彩色图像分析系统进行图像分析。结果:脊髓损伤后NGF表达升高,主要体现在白质部位,可见峰值为伤后7、15 d时灰质降至正常水平以下(P

Objective：To investigate The dynamic changes of nerve growth factor （NGF） Immunohistochemical expression in spinal cord injury with Incomplete paraplegia rabbit and the function of NGF in the spinal cord injury process. Methods：The method of oppression caused by the rabbit model of incomplete paraplegia, in 6 hours after injury, 7 days, 15 days take 3mm long tissue from spinal cord injury, with SP immunohistochemical staining, and Optimas6. 51 American color image analysis system for image AnalysisResults：NGF expression after spinal cord i...