Hypertension of liver-yang hyperactivity syndrome induced by a high salt diet by altering components of the gut microbiota associated with the glutamate/GABA-glutamine cycle

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成果类型：

期刊论文

作者：

Zheng, Tao;Wu, Yi;Peng, Mai-jiao;Xiao, Nen-qun;Tan, Zhou-jin;...

通讯作者：

Yang, T.

作者机构：

[Yang, Tao; Zheng, Tao] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha, Peoples R China.

[Peng, Mai-jiao; Xiao, Nen-qun; Zheng, Tao] Hunan Univ Chinese Med, Sch Pharm, Changsha, Peoples R China.

[Wu, Yi; Tan, Zhou-jin] Hunan Univ Chinese Med, Med Sch, Changsha, Peoples R China.

通讯机构：

College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, China

语种：

英文

关键词：

High salt diet;Hypertension;liver-Yang hyperactivity syndrome;Gut Microbiota;metabolite;Glutamate/GABA-glutamine cycle

期刊：

Frontiers in Nutrition

ISSN：

2296-861X

年：

2022

卷：

页码：

1721

DOI：

10.3389/fnut.2022.964273

基金类别：

Innovation and entrepreneurship training program for college students of Hunan Province, China [S202010541049]; Open fund of Key Laboratory of Agro-Products Processing, National Risk Assessment Laboratory of Agro-products Processing Quality and Safety, Ministry of Agriculture and Rural Affairs, P. R. China [S2020KFKT-18]; Hunan Provincial Science and Technology Department, China [2020SK2140]

机构署名：

本校为其他机构

院系归属：

医学院

药学院

摘要：

The gut microbiota and metabolites are closely related to hypertension; however, the changes in the composition of the gut microbiome and metabolites linking a high salt diet to elevated blood pressure are not established. In this study, traditional Chinese medicine (TCM) syndrome of hypertension caused by high salt had been diagnosed and the pathogenesis of hypertension was explored from the perspective of intestinal microecology. Rats in a high salt diet-induced hypertension group (CG) and normal group (CZ) were compared by 16S rRNA gene full...

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Hypertension of liver-yang hyperactivity syndrome induced by a high salt diet by altering components of the gut microbiota associated with the glutamate/GABA-glutamine cycle

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