Psoriasis is a recrudescent chronic immune-mediated inflammatory dermatosis; the production and release of proinflammatory cytokines/chemokines such as TNF-alpha has been regarded as critical issues during psoriasis pathogenesis. Based on online microarray profiles, the expression of the transcription factor GATA3 was downregulated in psoriasis lesion tissues. In the present study, we searched for miRNAs that might be related to TNF-alpha and GATA3 to investigate an in-depth understanding of psoriasis pathogenesis. Herein, higher TNF-alpha and GATA3 protein levels were observed in psoriasis le...
