Antibiotic-associated diarrhea(AAD)refers to the diarrhea related to antibiotics after the application of antibiotics,it is a common adverse drug reaction,and its pathogenesis has not been fully elucidated.Clostridium difficile(CD)is an anaerobic enteropathogen with spore structure,which is considered to be a common cause of AAD,more and more studies have shown that AAD is related to CD infection(CDI),but the mechanism of CD-induced AAD is not very clear.This paper elucidates the relationship between AAD and CD,analyzes the possible mechanism of CD-induced AAD and some currently existing treat...