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Phytochemistry, pharmacology and clinical applications of the traditional Chinese herb Pseudobulbus Cremastrae seu Pleiones (Shancigu): A review

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成果类型:
期刊论文
作者:
Jiang, Sai;Wang, Mengyun;Zafar, Salman;Jiang, Lin;Luo, Jiangyi;...
通讯作者:
Wang, W.
作者机构:
[Zhao, Huimin; Wang, Mengyun; Peng, Caiyun; Wang, Wei; Tian, Siying; Jiang, Sai; Luo, Jiangyi; Jiang, Lin; Zhu, Yuqing] Hunan Univ Chinese Med, Sch Pharm, Innovat Mat Med Res Inst, TCM & Ethnomedicine Innovat & Dev Int Lab, Changsha 410208, Peoples R China.
[Zafar, Salman] Univ Peshawar, Inst Chem Sci, Peshawar 25120, Pakistan.
[Jiang, Lin] Shanghai Jiao Tong Univ, Res Ctr Marine Drugs, Ren Ji Hosp, Sch Med,Dept Pharm,State Key Lab Oncogene & Relate, Shanghai 200000, Peoples R China.
[Wang, Wei] 300 Xueshi Rd,Hanpu Sci & Technol Pk, Changsha 410208, Peoples R China.
通讯机构:
300 Xueshi Rd., Hanpu Science & Technology Park, Yuelu District, Changsha, China
语种:
英文
关键词:
PCsP;Traditional uses;Phytochemistry;Pharmacological activities;Clinical applications;A549;Non-small-cell lung carcinoma;A2780;Ovarian cancer cell line;AKT;Protein Kinase B;Bax;BCL2-Associated X;BChE;Butyrylcholinesterase;Bcl-2;B-cell lymphoma-2;Bel7402;Liver cancer cell line;BGC-823;Human gastric carcinoma;CD-4+;Cluster differentiation 4+;Cyt-c;Cytochrome c;D-GalN;D-galactosamine;EC50;Half-maximal effective concentration;HCT-8;Human colon cancer cell line;HepG2;Human hepatocellular carcinoma;IC50;Half maximal inhibitory concentration;LA795;Mouse lung adenocarcinoma cells;MCF-7;Human breast cancer;MDA-MB-231;Human breast cell line;MTT;3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide;PC12;Pheochromocytomaderived cell line;ROS;Reactive oxygen species;SH-SY5Y;Human myeloid neuroblastoma;THP-1;Human acute monocytic leukemia cell line;VEGF;Vascular endothelial growth factor
期刊:
Arabian Journal of Chemistry
ISSN:
1878-5352
年:
2022
卷:
15
期:
9
页码:
104090
基金类别:
National Natural Science Foundation of China; Natural Science Foundation of Hunan Province; Pharmaceutical Open Fund of Domestic First-Class Disciplines (cultivation) of Hunan Province; Changsha Municipal Natural Science Foundation; [81874369]; [2020JJ4064]; [2020YX10]; [kq 2014086]
机构署名:
本校为第一机构
院系归属:
药学院
摘要:
Pseudobulbus Cremastrae seu Pleiones (PCsP) is a traditional Chinese herbal medicine known as "Shancigu" in China. It has the property of relieving fever, counteracting toxicity, dissi-pating phlegm and resolving masses. Officially recognized species of PCsP include Pleione bulboco-dioides (Franch.) Rolfe (PB), Cremastra appendiculata (D. Don) Makino (CA), and Pleione yunnanensis (Rolfe) Rolfe (PY). Approximately, 234 compounds have been isolated and identified from PCsP. The most thoroughly investigated constituents are stilbenes (bibenzyls and phenanthre-nes) and glucosyloxybenzyl succinate ...

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