Macrophage is a kind of immune cell which is closely related to atherosclerosis(As).With the change of internal environment,macrophage can polarize into different phenotype.Under the physiological environment,the po-larization of macrophages is in dynamic balance.In the As state,the polarization balance is destroyed and the correspond-ing phenotypic macrophages are differentiated,which play different roles in each stage of As.The debate between Zheng and Xie exists in the whole process of As formation and development,while macrophage polarization runs through the whole stage of As syndrome dif...
