National Natural Science Foundation of China [81800669]; Natural Science Foundation of Hunan Province [2021JJ40829]
机构署名：
本校为其他机构
院系归属：
针灸推拿与康复学院
摘要：
Introductions: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a poorly understood chronic disorder characterized by bladder-related pain. Chronic psychological stress plays a key role in the exacerbation and development of IC/BPS via unclear mechanisms. This study aimed to investigate the role of endothelin 1 (ET-1) and its receptors in the development of chronic stress-induced bladder dysfunction. Methods: Wistar-Kyoto rats were exposed to chronic (10 days) water avoidance stress (WAS) or sham stress, with subgroups receiving capsaici...
