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Changes of Serum Melatonin, Interleukin-6, Homocysteine, and Complement C3 and C4 Levels in Patients With Depression

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成果类型:
期刊论文
作者:
Tao, Huai;Chen, Xia;Zhou, Hongfei;Fu, Jinhua;Yu, Qi;...
通讯作者:
Liu, Y
作者机构:
[Zhou, Hongfei; Yu, Qi; Tao, Huai] Hunan Univ Chinese Med, Sch Med, Changsha, Peoples R China.
[Chen, Xia] Cent South Univ, Xiangya Hosp 2, Dept Orthoped, Changsha, Peoples R China.
[Fu, Jinhua] Hunan Prov Brain Hosp, Dept Psychiat, Changsha, Peoples R China.
[Liu, Yong] Cent South Univ, Xiangya Hosp 2, Dept Psychaitry,Hunan Key Lab Psychiat & Mental H, Natl Clin Res Ctr Mental Disorders,China Natl Tec, Changsha, Peoples R China.
通讯机构:
[Liu, Y ] C
Cent South Univ, Xiangya Hosp 2, Dept Psychaitry,Hunan Key Lab Psychiat & Mental H, Natl Clin Res Ctr Mental Disorders,China Natl Tec, Changsha, Peoples R China.
语种:
英文
关键词:
complement;depression;homocysteine;interleukin-6;melatonin
期刊:
FRONTIERS IN PSYCHOLOGY
ISSN:
1664-1078
年:
2020
卷:
11
页码:
543152
基金类别:
Funding. This work was supported by the National Natural Science Foundation of China (Nos. 81771448 and 81503276); the Hunan Provincial Natural Science Foundation of China (Nos. 2018JJ2580, 2018JJ3387, and 2015JJ4069); the Scientific Research Fund of Hunan Provincial Education Department (No. 15C1044); the Innovative Project for College Students in Hunan Province (2017–310) and Hunan University of Chinese Medicine (2016–21); the First-class Discipline Construction Project of basic medicine in 13th Five-Year Plan of Hunan University of Chinese Medicine (No. 06); and the traditional Chinese Medicine Scientific Research Project of Hunan Province (No. 2015109).
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Objectives: Cytokine activation and low complement levels are common in depression patients. This study is aimed at investigating the clinical significance of changes in serum concentrations of melatonin (MT), interleukin-6 (IL-6), homocysteine (hcy), and complement C3 and C4 in depression patients and relationships of them with depression activity. Methods: A total of 95 depression patients, including first-episode group (n = 43) and recurrent group (n = 52), and 45 age- and gender-matched healthy controls (HC) were recruited. Serum levels of ...

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