期刊论文

Analysis of TCM deficiency and excess attributes in patients with HBV- related acute- on- chronic liver failure based on phenotype of dendritic cells and function of T lymphocytes

中文

临床肝胆病杂志

1001-5256

2016

32

4

663-668

10.3969/j.issn.1001-5256.2016.04.010

国家自然基金青年基金项目（81102594/H2708） 湖南省高校科技创新团队“感染性疾病中医药防治研究”及中央财政支持地方高校发展专项建设项目（Grxjb-2） 中医诊断国家重点学科开放基金（2013ZYZD11）

本校为第一机构

目的 归纳HBV相关慢加急性肝衰竭(HBV-ACLF)的中医虚实属性,分析其与树突状细胞(DC)表型及T淋巴细胞亚群的关系.方法 收集2012年3月-11月于湖南中医药大学第一附属医院就诊的30例HBV-ACLF患者的基本资料、分期、中医证候等,归纳其中医虚实属性,分为实证组和虚证组;另选同期健康研究生志愿者10例作为对照组.应用流式细胞仪检测外周血CD3+、CD4+、CD8+T淋巴细胞百分比、CD4+ CD25high CD127low表达率,以及外周血单个核细胞体外分离诱导培养的DC表型CD1α、HLA-DR、CD80、CD83、CD86表达率.计量资料符合正态分布的组间比较采用t检验,非正态分布的组间比较采用Wilcoxon秩和检验;计数资料组间比较用x...

Objective To summarize the traditional Chinese medicine（ TCM） deficiency and excess attributes in patients with HBV- related acute- on- chronic liver failure（ HBV- ACLF）,and to analyze its association with the phenotype of dendritic cells（ DCs） and T lymphocyte subsets. Methods The basic information,stages,and TCM syndromes of 30 patients who were diagnosed with HBV- ACLF in The First Affiliated Hospital of Hunan University of Chinese Medicine from March to November,2012 were collected,and according to their deficiency and excess attribut...