Objective ： To explore the effect and possible mechanism of Andrographis decoction in the treatment of allergic rhinitis. Methods： All guinea pigs were randomly divided into five groups, blank group, model group, Andrographis group, cetirizine group and combination group. Then we treated these groups with the appropriate drug lavage interven- tion. HE, ELISA, RT - PCR were used to observe the pathological changes of nasal mucosa and lung tissue, the content of cytokines in serum and the mRNA expression of Timl and Tim3 in lung tissue of each ...
