Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Huang, Lu;Peng, Zhuang;Lu, Cong;Chen, Ying;Lv, Jing-wei;...

通讯作者：

Liao, Duan-fang;Liu, Xin-min;Shi, Zhe

作者机构：

[Huang, Lu; Peng, Zhuang; Liao, Duan-fang; Shi, Zhe; Liao, DF; Liu, Xin-min; Shi, Z] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, Key Lab Qual Evaluat Bulk Herbs Hunan Prov, Changsha 410208, Hunan, Peoples R China.

[Huang, Lu] Jinan Univ, Guangdong Hongkong Macau Inst CNS Regenerat, Minist Educ, CNS Regenerat Collaborat Joint Lab, Guangzhou 510632, Peoples R China.

[Lv, Jing-wei; Lu, Cong; Liu, Xin-min] Chinese Acad Med Sci & Peking Union Med Coll, Res Ctr Pharmacol & Toxicol, Inst Med Plant Dev IMPLAD, Beijing 100193, Peoples R China.

[Chen, Ying] China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China.

[Peng, Zhuang; Qin, Meng] Beijing Univ Chem Technol, Coll Life Sci & Technol, Beijing 100029, Peoples R China.

通讯机构：

[Liao, DF; Liu, XM; Shi, Z] H

[Liu, Xin-min] C

Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, Key Lab Qual Evaluat Bulk Herbs Hunan Prov, Changsha 410208, Hunan, Peoples R China.

Chinese Acad Med Sci & Peking Union Med Coll, Res Ctr Pharmacol & Toxicol, Inst Med Plant Dev IMPLAD, Beijing 100193, Peoples R China.

语种：

英文

关键词：

Ginsenoside Rg1;Repeated alcohol exposure;Psychomotor and cognitive deficits;Excitatory glutamatergic transmission;NR2B containing NMDARs

期刊：

Chinese Medicine

ISSN：

1749-8546

年：

2020

卷：

期：

页码：

1-11

DOI：

10.1186/s13020-020-00325-x

基金类别：

Scientific Research Fund of Hunan Provincial Education [19B422]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2019T120788, 2018M643369]; Postdoctoral Fund of the First Affiliated Hospital, Jinan University [801324]; National Science and Technology Major Project [2017ZX09101002-002-008]

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

Background Chronic alcohol consumption disrupts psychomotor and cognitive functions, most of which are subserved by the dysfunction of hippocampus. Dysregulated excitatory glutamatergic transmission is implicated in repeated alcohol induced psychomotor and cognitive impairment. Ginsenoside Rg1, one of the main active ingredient of the traditional tonic medicine Panax ginseng C.A. Meyer (Araliaceae), has been used to treat cognitive deficits. Particularly, Rg1 has been demonstrated to improve hippocampus-dependent learning in mice and attenuate glutamate-induced excitotoxicity in vitro. Thus, i...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问