期刊论文

Effects of electroacupuncture preconditioning of"Neiguan"(PC 6)on myocardial ischemia reperfusion injury via Akt/mTOR pathway

中文

国际中医中药杂志

1673-4246

2023

45

6

703-708

10.3760/cma.j.cn115398-20221101-00027

湖南省自然科学基金项目(2021JJ30507)。

本校为第一机构

目的观察电针预处理对心肌缺血再灌注损伤(MIRI)模型大鼠心肌组织自噬相关通路Akt/mTOR的影响,探讨电针“内关”对心肌损伤的作用机制。方法将48只SD大鼠按随机数字表法分为空白组、假手术组、模型组和内关组,每组12...展开更多 目的观察电针预处理对心肌缺血再灌注损伤(MIRI)模型大鼠心肌组织自噬相关通路Akt/mTOR的影响,探讨电针“内关”对心肌损伤的作用机制。方法将48只SD大鼠按随机数字表法分为空白组、假手术组、模型组和内关组,每组12只。内关组电针刺激大鼠“内关”,每次30 min,1次/d,连续干预7 d。干预结束后,除空白组外,其余各组大鼠采用冠状动脉左前降支结扎法建立MIRI模型。采用HE染...

Objective To observe the effects of electroacupuncture preconditioning on the autophagy-related pathway protein kinase B(Akt)/mammalian target of rapamycin(mTOR)in myocardial tissue of rats with myocardial ischemia reperfusion injury(MIRI);To investigate the protective ...MORE Objective To observe the effects of electroacupuncture preconditioning on the autophagy-related pathway protein kinase B(Akt)/mammalian target of rapamycin(mTOR)in myocardial tissue of rats with myocardial ischemia reperfusion injury(MIRI);To investigate the protective mechanism of"Neiguan"(PC 6)on myocardial injury.Meth...