期刊论文

Discussion on the medication law of TCM compound patents in treating diabetic retinopathy based on data mining

中文

国际中医中药杂志

1673-4246

2023

45

11

1448-1452

10.3760/cma.j.cn115398-20220923-00331

本校为第一机构

目的:探究中药复方专利治疗糖尿病视网膜病变（DR）的用药规律。方法:检索中国知识资源总库（CNKI）专利数据库建库至2022年9月1日公开发表的治疗DR的中药复方专利，采用古今医案云平台V2.0对用药频次与性味、归经分布进行分析，基于关联规则与聚类分析方法对配伍用药规律进行挖掘分析。结果:共纳入复方专利113个，包括中药201味，其中使用频次排名前5位依次为生地黄、三七、当归、灵芝、黄芪，用药药性以寒、温居多，药味以甘、苦为主，归经多为肝、肺、肾经。常用药对6对，聚类分析得出4类药物；复杂网络分析得到核心中药组合为生地黄、三七、当归、灵芝、黄芪、丹参、枸杞子、蕤仁、菟丝子。...

Objective:To explore the law of Chinese medicine patent compound prescription in treating diabetic retinopathy (DR).Methods:The patents of TCM compound for the treatment of DR Published in the patent database of China National Knowledge Resource Database (CNKI) from the establishment of the database to September 1, 2022 were searched and screened. The Ancient and Modern Medical Record Cloud Platform V2.0 was used to analyze the frequency of medication, nature, taste, and meridian distribution, and the rules of compatibility of medication were mined and analyzed based on association rules and c...