This research was supported by the Diagnosis and Treatment Enhancement Project of Hunan Provincial Severe Mental illness (2018SK70020), and First class Discipline in Clinical Medical School of Hunan University of Chinese Medicine, and a grant of the National Natural Science Youth Found of the Hunan Province (2018JJ3284 to XZ), and a grant of the National Key research and development program (2018YFC1314401 to XZ), and a grant of the Scientific Research Project of Hunan Provincial Health Commission (20200620 to XZ), and a grant of the Hunan Research Center for Mental and Behavioral Disorders (2018SK70020 to XZ), and Provincial technology innovation guide program funded by the Hunan Department of Science and Technology (2017SK50312 to CL), and by Outstanding Young program funded by the Hunan Province Department of Education (18B254 to CL), and a grant of the Ministry of Education of China for Outstanding Young Teachers in University, a grant of the National Natural Science Foundation of Hunan Province (2019JJ80028 to LX).