Molecular mechanism of vascular remodeling in hypertension and Chinese medicine intervention
作者:
张婵娟;石雅宁;廖端芳;杜可;覃丽
通讯作者:
Qin, Li
作者机构:
[杜可] Department of Pharmacology, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China
[廖端芳] Division of Stem Cell Regulation and Application, Hunan University of Chinese Medicine, Changsha, 410208, China
[张婵娟; Qin L.; 石雅宁] Department of Pharmacology, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China, Division of Stem Cell Regulation and Application, Hunan University of Chinese Medicine, Changsha, 410208, China
通讯机构:
[Qin, Li] D
Division of Stem Cell Regulation and Application, Hunan University of Chinese Medicine, Changsha 410208, China.
语种:
中文
关键词:
血管重塑;高血压;中医药;分子机制
关键词(英文):
hypertension;traditional Chinese medicine;molecular mechanism
Vascular remodeling is a significant pathological characteristic of hypertension,which is regulated by complex regulatory networks.The vascular remodeling may be adaptive initially,however it becomes maladaptive and decompensation eventually and further compromises target organ function,leading to hypertensive cardiovascular complications.This review focuses on the role and mechanisms of vascular remodeling in the pathogenesis and progression of hypertension and its complications.Moreover,the strategies of syndrome differentiation of traditional Chinese medicine application provide clinical an...