National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81573985, 81774326]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2017JJ2207]
机构署名：
本校为第一且通讯机构
院系归属：
第二中医临床医学院
摘要：
BACKGROUND: During psoriasis initiation and development, deregulations in signaling pathways and gene expression are observed. METHODS: Herein, we downloaded seven sets of microarray mRNA expression profiles showing differentially-expressed genes in psoriasis lesion skin and non-lesion skin tissues and three sets of RNA-seq data and analyzed these online data attempting to screen for crucial genes related to keratinocyte proliferation and psoriasis development. The expression of CTNNBIP1 in psoriasis patients and IMQ mouse model skin tissues we...
