期刊论文

Tan, Z.

中文

应用与环境生物学报

1006-687X

2015

21

1

61-67

10.3724/SP.J.1145.2013.10002

国家自然科学基金项目（81173214）资助~~；

本校为第一且通讯机构

探讨超微七味白术散与酵母菌联用对菌群失调腹泻的疗效, 可为超微七味白术散与酵母菌配伍制剂的研发提供依据.采用抗生素建立小鼠菌群失调腹泻模型, 灌胃给药七味白术散50%量超微汤药、50%量超微汤药+12.5%量酵母、25%量超微汤药+25%量酵母、12.5%量超微汤药+50%量酵母及全量酵母, 比较分析小鼠体重变化率、免疫器官指数、肠道菌群数及酶活.结果表明, 超微七味白术散和酵母菌对小鼠体重和脾脏无显著影响, 各治疗组的胸腺指数为正常水平(P > 0.05);超微七味白术散和酵母菌均能促进双歧杆菌和乳酸菌的生长(P < 0.01), 调节微生态平衡;50%量超微汤药组和25%量超微汤药+25%量酵母组的大肠杆菌、细菌...

This research aimed to provide scientific basis for preparation development of ultra-micro powder Qiweibaizhusan combined with yeast by exploring its clinic effect on dysbacteriotic diarrhea. First, dysbacteriotic diarrheal mice model was constructed via administration of antibiotics. The modeled mice were treated with 50% amount of ultra-micro Qiweibaizhusan, 50% amount of ultra-micro Qiweibaizhusan + 12.5% amount of yeast, 25% amount of ultra-micro Qiweibaizhusan + 25% amount of yeast, 12.5% amount of ultra-micro Qiweibaizhusan + 50% amount of yeast, and yeast alone, respectively. The body w...