Ischemic stroke leads to serious brain injury,which is one of the main causes of death and disability in the world.Neuronal damage has been a hot research topic in a series of complex molecular mechanisms after ischemic stroke.Ubiquitination is a kind of post-translational protein modification with multiple cellular proteins as degradation targets,which is strictly regulated and essential for the cell survival.Ubiquitination is closely related to the occurrence and development of a variety of nervous system diseases,and many nervous system diseases show the aggregation of ubiquitination protei...
