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Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats

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成果类型:
期刊论文
作者:
Zhang, Ling;Fan, Xin-Rong*;Xie, Hui;He, Qing-Hu(何清湖);Nie, Yu-Song;...
通讯作者:
Yan, Miao;Fan, Xin-Rong
作者机构:
[Yan, Miao; Zhang, Ling] Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha 410011, Hunan, Peoples R China.
[Zhang, Ling; Fan, Xin-Rong] China Acad Chinese Med Sci, Inst BasicTheory Chinese Med, Beijing 100700, Peoples R China.
[He, Qing-Hu; Nie, Yu-Song; Zhang, Ling; Fan, Xin-Rong; Xie, Hui] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.
[Zhang, Min] Shanxi Univ Chinese Med, Clin Med Coll 1, Xianyang 712000, Shanxi, Peoples R China.
通讯机构:
[Yan, Miao; Fan, Xin-Rong] C
[Fan, Xin-Rong] H
Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha 410011, Hunan, Peoples R China.
China Acad Chinese Med Sci, Inst BasicTheory Chinese Med, Beijing 100700, Peoples R China.
Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.
语种:
英文
期刊:
Evidence-Based Complementary and Alternative Medicine
ISSN:
1741-427X
年:
2018
卷:
2018
页码:
5290514
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81373708, 81573686]
机构署名:
本校为通讯机构
院系归属:
中西医结合学院
摘要:
Benign prostatic hyperplasia (BPH) is a common disease in the current ageing male population. This research aims to study the effects of Kelong-Capsules (KLC) on testosterone-induced BPH. Thirty rats were randomly divided into normal group, model group, and three treatment groups. Three treatment groups were given KLC (3.6 g/kg), KLC (7.2 g/kg), and finasteride (0.9 mg/kg), respectively, for 28 days after establishing the animal model. The BPH rat models were evaluated by Traditional Chinese Medicine (TCM) symptoms and prostate index (PI). Resu...

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