Objectives To explore the feasibility of application of real patients act as standardized patients in the prac-tical teaching for diagnostics of traditional Chinese medicine. Methods 45 students of our school level 2014 in Class 2 pro-fessional year 7 of integration of traditional and western medicine major were involved in the study. According to the arrange-ment, they were required to complete the practical teaching task by using Inquiry and diagnostic method and syn-drome differentiation on the real patients act as the standardized patients, the practice effect was fed back by means of prac...