期刊论文

Cai, Xiong;Wang, Wei

英文

Journal of Ethnopharmacology

0378-8741

2019

238

111902

10.1016/j.jep.2019.111902

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81874369, 81703819, 81704065, 81673579]; Hunan Provincial Natural Science FoundationNatural Science Foundation of Hunan Province [2017JJ3239, 2018JJ2293]; Hunan Education Department's Science & Research Project [17K069, 17A157]; Hunan Provincial Science & Research Project of Chinese Medicine [201790, 201909]; Hunan Provincial Innovation Project for Outstanding Postgraduate Students [CX2018B476]; Open Foundation Project of Hunan Provincial Key Laboratory of Druggability and Preparation Modification for Chinese Medicine [201701]; 121 Hunan Provincial Training Project for Innovative Talents of Hunan University of Chinese Medicine; National First-class Disciple Construction Project of Chinese Medicine of Hunan University of Chinese Medicine; 2015 Program for Innovative Research Team of Hunan University of Chinese Medicine

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ETHNOPHARMACOLOGICAL RELEVANCE: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by failure of spontaneous resolution of inflammation. The stem of Kadsura heteroclite (KHS) is a well-known anti-arthritic Tujia ethnomedicinal plant, which named Xuetong in folk, has long been used for the prevention and treatment of rheumatic and arthritic diseases. AIM OF THE STUDY: The analgesic and anti-inflammatory effects and the potential mechanisms behind such effects of KHS would be investigated by using different animal models. MATERIALS AND METHODS: The abdominal writhing episode...