National Natural Sciences Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81573985]; Chinese medicine research project of Hunan Province [2016137, 2016127]
机构署名:
本校为第一机构
院系归属:
第二中医临床医学院
摘要:
Chronic skin inflammation in atopic eczema is associated with elevated expression of proinflammatory genes and activation of innate immune responses in keratinocytes. MicroRNAs (miRNAs) are short, single-stranded RNA molecules that silence genes via the degradation of target mRNAs or inhibition of translation. Recent studies have demonstrated that miR-124 is associated with regulation of inflammation factors in several diseases. The aim of this study was to investigate the role of miR-124 in skin inflammation of atopic eczema. We showed that mi...