Guizhou Province Traditional Chinese Medicine Administration, National Medical Science and Technology Research Project [QZYY-2019-021]; Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Research projects in the hospital [GZEYK[2020]11]; Guizhou University of Traditional Chinese Medicine 2019 Campus Project
机构署名：
本校为通讯机构
院系归属：
第二中医临床医学院
摘要：
Ischemic stroke (IS) is a common disease that seriously endangers human health. Patients with IS present with increased death of brain microvascular endothelial cells (BMECs). MALAT1 is found to be upregulated in IS patients. However, the function of MALAT1 in IS pathogenesis still remains unclear. This study aimed to investigate the role of MALAT1 in IS in vitro model and the related molecular mechanisms. The expressions of MALAT1 and miR-126 were detected by qPCR. The in vitro IS model was established by treating BMECs with oxygen-glucose deprivation (OGD). Cell viability and cell apoptosis ...
