期刊论文

Effect of ultra-micro powder qiweibaishusan on the intestinal microbiota and enzyme activities in mice

Tan, Z.

中文

生态学报

1000-0933

2012

32

21

6856-6863

10.5846/stxb201109271422

国家自然科学基金（81173214） 湖南省科技厅重点项目（2010SK2002） 湖南省研究生科研创新项目（CX2010B348）

本校为第一且通讯机构

肠道微生物与人体多项生理功能密切相关,为探讨超微七味白术散疗效与肠道微生物及酶活性的关系,为中药复方超微饮片临床应用提供科学依据,运用抗生素建立菌群失调小鼠模型,分别灌胃给药七味白术散传统汤剂、超微全量汤剂、超微1/2量汤剂、超微1/4量汤剂、超微1/8量汤剂,分析肠道菌群数及酶活性。结果表明,模型组的肠道微生物（细菌、大肠杆菌、酵母菌、霉菌、乳酸菌及双歧杆菌）数量、木聚糖酶活、蛋白酶活及淀粉酶活均低于对照组（P

The physiological functions of the human body are influenced by intestinal microbiota. To provide scientific evidence for the clinical effectiveness of ultra-micro decoction pieces of traditional Chinese medicine (specifically the effect of ultra-micro Qiweibaishusan on intestinal microbiota and enzyme activities), mice were rendered dysbacteriotic via administration of antibiotics and then treated with traditional Qiweibaishusan. The effects of the full amount, 1/2 the amount, 1/4 the amount, and 1/8 amount of ultra-micro Qiweibaishusan on the intestinal microbiota and enzyme activities were ...