Objective To explore the effect of asparagus on intestinal microorganisms and enzyme activity of mice fed with high-fat diet mice, and provide basis for the application of asparagus. Methods The mice were randomly divided into the normal group, high-fat diet group, low-dose asparagus group, medium-dose asparagus group, high-dose asparagus group, or positive control group. The normal group was fed normal feed, while the rest groups were fed high-fat feed. Distilled water (normal group, high-fat diet group), asparagus 1.05 g/(kg·d) (low-dose asp...