期刊论文

Effects of electroacupuncture specific acupoint on Shaoyang meridians on the behavior,50%PWT and serum 5-HT,SP content in migraine rats in different periods

中文

时珍国医国药

1008-0805

2019

30

11

2795-2798

10.3969/j.issn.1008-0805.2019.11.082

中国博士后科学基金面上项目(2017M612566) 湖南省自然科学基金面上项目(2019JJ40227) 湖南省研究生科研创新项目(2018CX47) 第四批全国中医临川基础优秀人才研修项目(国中医药人教发[2017]24号) 湖南省***卫生人才225工程培养项目。

本校为第一机构

目的观察不同时期电针少阳经特定穴对偏头痛大鼠的行为学、50%缩足阈值(50% PWT)及血清中5-羟色胺(5-HT),P物质(SP)含量的影响,为临床运用针灸治疗偏头痛选择合理方案。方法将50只大鼠随机分为空白组(A组)、模型组(B组)、电针少阳经穴预防组(C组)、电针少阳经穴治疗组(D组)、电针少阳经穴预防+治疗组(E组)共5组,每组10只。C组和E组捆绑行电针治疗30 min ×7天,其余各组同时段捆绑30 min,7天。A组第8天皮下注射等量0.9%氯化钠注射液,30 min后捆绑30 min;其余各组第8天皮下注射硝酸甘油造模,其中B组、C组造模30 min后捆绑30 min,D、E组造模30 min后捆绑行电针治疗30 min。观察造模前后及治疗后大鼠...

Objective To observe the effect of electroacupuncture on the behavior of migraine rats,50% Paw Withdrawal Threshold(PWT) and the content of 5-hydroxy tryptamine(5-HT) and Substance p(SP) in serum in different periods,and to select a reasonable plan for the clinical use of acupuncture for the treatment of migraine.Methods Fifty rats were randomly divided into five groups (group A),model group (group B),electroacupuncture Shaoyang acupoint prevention group (group C),electroacupuncture Shaoyang acupoint treatment group (group D) and electroacupuncture Shaoyang acupoint prevention and treatment gr...