期刊论文

Effect of acupuncture on the expression of miR-29a-3p and miR-29b-3p in hippocampal tissue of rats with cerebral ischemia-reperfusion injury

中文

时珍国医国药

1008-0805

2024

35

2

485-488

10.3969/j.issn.1008-0805.2024.02.64

82274662:国家自然科学基金 2021JJ30490:湖南省自然科学基金项目 kq2014094:湖南省长沙市科技局自然科学基金项目 2022CX103:湖南省研究生科研创新项目

本校为第一机构

目的观察针刺干预72 h后脑缺血再灌注损伤(CIRI)大鼠缺血侧海马区miR-29a-3p、miR-29b-3p的表达,探讨针刺促CIRI修复的机制。方法30只SD大鼠随机分为假手术组、模型组和针刺组,每组10只,造模组...展开更多 目的观察针刺干预72 h后脑缺血再灌注损伤(CIRI)大鼠缺血侧海马区miR-29a-3p、miR-29b-3p的表达,探讨针刺促CIRI修复的机制。方法30只SD大鼠随机分为假手术组、模型组和针刺组,每组10只,造模组大鼠使用线栓法制备CIRI模型,假手术组只剥离血管不插入线栓;假手术组和模型组只捆绑不针刺,针刺组捆绑后针刺“大椎”“百会”“水沟”穴,一天治疗两次,共治疗7次。采用Garcia评分法对神经功能进行评...

Objective To observe the expression of miR-29a-3p and miR-29b-3p in the hippocampal region of the ischemic side of rats with cerebral ischemia-reperfusion injury(CIRI)after 72 h of acupuncture intervention,and to explore the mechanism of acupuncture to promote anti-CIRI...MORE Objective To observe the expression of miR-29a-3p and miR-29b-3p in the hippocampal region of the ischemic side of rats with cerebral ischemia-reperfusion injury(CIRI)after 72 h of acupuncture intervention,and to explore the mechanism of acupuncture to promote anti-CIRI repair.Methods Thirty SD rats were randomized to sh...