Identification and validation of a novel cuproptosis-related genes signature associated with prognosis, clinical implications and immunotherapy of hepatocellular carcinoma

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

He, Fengjiao;Zeng, Puhua;Ma, Sijing;Yang, Ximing;Liu, Huan;...

通讯作者：

Zhou, Y.;Zhu, H.

作者机构：

[Liu, Huan; Zhu, Hong; Liu, Qiong; Zhou, Yangying; He, Fengjiao] Cent South Univ, Xiangya Hosp, Dept Oncol, Changsha, Peoples R China.

[Liu, Huan; Zhu, Hong; Liu, Qiong; Zhou, Yangying; He, Fengjiao] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China.

[Zeng, Puhua; Ma, Sijing; He, Fengjiao] Hunan Acad Tradit Chinese Med Affiliated Hosp, Changsha, Peoples R China.

[Yang, Ximing] Hunan Univ Chinese Med, Med Sch, Changsha, Peoples R China.

通讯机构：

[Zhou, Y.; Zhu, H.] D

Department of Oncology, China

语种：

英文

关键词：

cuproptosis-related genes;drug sensitivity;hepatocellular carcinoma;prognosis model;tumor microenvironment

期刊：

Frontiers in Pharmacology

ISSN：

1663-9812

年：

2023

卷：

页码：

1088993

DOI：

10.3389/fphar.2023.1088993

基金类别：

This work was supported by the National Natural Science Foundation of China (81803787, 82203353), the Fellowship of China Postdoctoral Science Foundation (2022M723565), the Natural Science Foundation of Hunan Province (2022JJ40851), the Health Commission Foundation of Hunan Province (202202085327), and the Traditional Chinese Medicine Administration Foundation of Hunan Province (2021069).

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Background: Cuproptosis is a novel type of regulated cell death and is reported to promote tumor occurrence and progression. However, whether a cuproptosis-related signature has an impact on hepatocellular carcinoma (HCC) is still unclear. Materials and methods: We analyzed the transcriptome data of HCC from The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) database, and searched for tumor types with different cuproptosis patterns through consistent clustering of cuproptosis genes. We then constructed a Cuproptosi...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Identification and validation of a novel cuproptosis-related genes signature associated with prognosis, clinical implications and immunotherapy of hepatocellular carcinoma

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问