期刊论文

Yi Zhang

英文

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

1046-7408

2025

93

5

e70091

10.1111/aji.70091

Yi Zhang, Lulu Wu, Wanjing Yuan, and Zhen Ren contributed equally to this work. This study was supported by funding from the Scientific Research Project of the Hunan Provincial Health Commission (No. D202305017387), the Natural Science Foundation of Hunan Province (No. 2024JJ9444), and the Scientific Research Project of the Hunan Provincial Administration of Traditional Chinese Medicine (No. A2024039).

本校为第一且通讯机构

OBJECTIVE: This study aimed to identify and validate potential immune-related genes in endometriosis (Ems) through comprehensive bioinformatics analysis and immunohistochemistry (IHC) verification. DESIGN: Using data from the GEO database, single-cell RNA sequencing (scRNA) data and traditional bulk RNA sequencing data were analyzed to identify differentially expressed genes related to the immune system. Immunological analysis confirmed alterations in immune cells associated with Ems. Machine learning techniques were employed to identify characteristic immune genes of eutopic and ectopic endom...