Objective: The aim of this study was to develop a new mouse cerebral infarction model based on vascular endodielial damage, leading to small cerebral infarcts and neurological deficits in rats. Methods: Eleven Sprague-Dawley rats was used in the present study. Rats was anesthetized with sodium pentobarbital, and 150μg of sodium lautate was injected into the left internal carotid artery. The consequent of ischemic brain damage was examined by histopathological analyses. The area of cerebral infarction was calculated after sections of cerebrum w...