期刊论文

中文

中医杂志

1001-1668

2013

54

22

1922-1925

10.13288/j.11-2166/r.2013.22.026

国家“十一五”传染病重大专项课题资助项目

本校为其他机构

目的观察中西医结合治疗方案对慢加急性(亚急性)肝衰竭患者病死率的影响。方法将来自20个中心的511例患者随机分为治疗组(给予基础治疗+中医药辨证治疗+对症支持治疗)360例与对照组(给予基础治疗+对症支持治疗)151例,两组均治疗8周,随访至第48周。治疗后判定两组临床疗效,并于治疗后第8、12、24、48周观察两组的病死率。结果治疗组治疗第8、12、24、48周病死率分别为20.99%、22.61%、23.06%、25.99%,对照组分别为30.87%、32.21%、34.23%、34.23%,治疗组各时间点病死率均低于对照组(P

Objective To observe the effect of integrative medicine on the mortalit in patients with acute-on- chronic (subacute) liver failure. Methods A prospective, multicenter and randomized controlled study was conducted to randomize 511 patients into the treatment group (basic therapy + TCM treatment + symptomatic and supportive treatment) and control group (basic therapy + symptomatic and supportive treatment), with 360 and 151 in each. Both groups were treated for 8 weeks and followed up to the 48th week. The mortality rate and survival time was observed in the 8th, 12th, 24th and 48th week after ...