期刊论文

Chang Xiaorong

英文

中医杂志(英文版)

0255-2922

2015

35

1

90-98

10.1016/S0254-6272(15)30014-5

Supported by the Study of Warming Effect of Moxibustion and its Principle （the Major National Basic Research Program of China, No. 2009CB522904） and the Study of Safety of Moxibustion Products Based on High Performance Liquid Chromatography-Mass Spectrometry in Metabonomics Technology （Hunan Graduate Student Innovation Fund, No. CX2010B342）

本校为第一且通讯机构

OBJECTIVE: To design a combined dynamic inhalation device for testing the toxicity induced by moxa smoking.METHODS: The new apparatus (Patent No.201120101911.5) includes air renewal and recycling systems, a gas generating device, a gas control unit, and a device to measure and control temperature and humidity. Sprague-dawley rats were tested for acute and sub-chronic toxicity after exposure to moxa-burning smoke.RESULTS: We found an LC_(50) of 1.2 × 10~4 mg/m~3 in the acute toxicity assays. In sub-chronic toxicity tests the organ coefficients ...