Objective To explore the possible mechanism of Yishen Huoxue Zhitong Decoction（ 益肾活血止痛方）in the treatment of bone metastases. Methods A total of 40 SD rats were randomly divided into Chinese medicine group,zoledronic acid group,model group and sham operation group,with 10 rats in each group. Except the sham operation group,3 μl of rat breast cancer Walker 256 cell suspension was slowly injected into the bone marrow cavity of rat tibia to establish a bone metastasis model in other groups. The drug was administered on the 5 th day after ...
