Objective To investigate the possible mechanism of Zuogui Jiangtang Tongmai Formulae (ZGJTTMF) (左归降糖通脉方) in the treatment of diabetic vascular complications. Methods Thirty rats were randomly divided into the blank group,the Chinese medicine group and the western medicine group,with 10 rats in each group. The Chinese medicine group was intragastrically given ZGJTTMF 36 g/(kg·d) ,and the western medicine group was given nimodipine tablets 18. 35 mg/(kg·d) and gliclazide sustained-release tablets 27. 5 mg/(kg·d) by gavage. The blank gro...