期刊论文

Effect of Xiaoke Formula (消渴方) on Ca~(2+) /CaN/NFAT Signaling Pathway in Pancreatic Tissue of Type 2 Diabetes Mellitus Model Rats

中文

中医杂志

1001-1668

2021

62

17

1526-1532

10.13288/j.11-2166/r.2021.17.012

湖南省自然科学基金（2018JJ6037）； 第六批全国老中医药专家学术经验继承培训项目（国中医药人教发[2017]125号）； 湖南中医药大学研究生科研创新课题（2018CX48）；

本校为第一机构

Objective To explore the possible mechanism of Xiaoke Formula (消渴方) for type 2 diabetes mellitus ( T2DM). Methods High-fat and high-sugar feed combined with intraperitoneal injection of 35 mg /kg 2% streptozotocin-citrate buffer were used to establish the T2DM rat model. Forty successfully modeled rats were randomly divided into model group,inhibitor group,Xiaoke Formula group,Xiaoke Formula plus inhibitor group ( combination group),with 10 rats in each group; and another 10 SD rats were set as the normal group. After modeling,rats in the Xi...