版权说明 操作指南
首页 > 成果 > 详情

The role of NLRP3 inflammasome-mediated pyroptosis in ischemic stroke and the intervention of traditional Chinese medicine

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Long, Jia-Xin;Tian, Meng-Zhi;Chen, Xiao-Yi;Yu, Huang-He;Ding, Huang;...
通讯作者:
Du, K
作者机构:
[Du, Ke; Du, K; Yu, Huang-He; Tian, Meng-Zhi; Chen, Xiao-Yi; Liu, Fang; Long, Jia-Xin] Hunan Univ Chinese Med, Sch Pharm, Changsha, Peoples R China.
[Ding, Huang] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese Med & Western Med, Changsha, Peoples R China.
通讯机构:
[Du, K ] H
Hunan Univ Chinese Med, Sch Pharm, Changsha, Peoples R China.
语种:
英文
关键词:
Ischemic stroke (IS);pyroptosis;NLRP3;pathways;Traditional Chinese medicine (TCM)
期刊:
Frontiers in Pharmacology
ISSN:
1663-9812
年:
2023
卷:
14
页码:
1151196
基金类别:
This work was supported by State Key Laboratory Open Program of China (GTZK201711), Hunan Provincial Natural Science Foundation of China (2020JJ9050), Double-class Discipline Pharmacy Open Fund of China (2018YX03), Hunan Provincial Department of Education Postgraduate Innovation and Entrepreneurship Training Program Project of China (CX20220794), Innovation and Entrepreneurship Training Program for College Students of Hunan Provincial Department of Education of China (S202210541074), First-class undergraduate courses in Hunan Province of China (2021(28)-371) and Research project of educational reform in universities in Hunan Province of China (HNJG-2022-0134).
机构署名:
本校为第一且通讯机构
院系归属:
药学院
摘要:
Ischemic stroke (IS) is the second leading cause of death and disability in the world. Pyroptosis, a form of programmed cell death initiated by caspases, participates in the occurrence and development of IS. Because it can increase cell membrane permeability, mediate the release of inflammatory factors, and aggravate inflammation, inhibiting this process can significantly reduce the pathological injury of IS. The nucleotide binding oligomerization domain-like receptor family pyrin domain protein 3 (NLRP3) is a multiprotein complex whose activat...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com