This work was supported by State Key Laboratory Open Program of China (GTZK201711), Hunan Provincial Natural Science Foundation of China (2020JJ9050), Double-class Discipline Pharmacy Open Fund of China (2018YX03), Hunan Provincial Department of Education Postgraduate Innovation and Entrepreneurship Training Program Project of China (CX20220794), Innovation and Entrepreneurship Training Program for College Students of Hunan Provincial Department of Education of China (S202210541074), First-class undergraduate courses in Hunan Province of China (2021(28)-371) and Research project of educational reform in universities in Hunan Province of China (HNJG-2022-0134).