期刊论文

中文

湖南中医药大学学报

1674-070X

2005

25

5

12-13,20

10.3969/j.issn.1674-070X.2005.05.004

C30271633:中国科学院项目（非规范项目）

本校为第一机构

目的探讨三七不同有效成分干预人子宫内膜炎症模型后,其细胞培养液中一氧化氮(NO)和一氧化氮合酶(NOS)活力的变化.方法以三七有效成分干预炎症子宫内膜细胞模型,分别测定48h及72 hNO、NOS的活力.结果模型组细胞培养液中NO、NOS活力较正常对照组明显增高(P＜0.01).经药物干预后,三七复方组和三七氨酸组NO和NOS活力都明显低于同时段的模型组(P＜0.01).而48h三七皂苷组与同时段模型组比较,NO含量、NOS活力明显升高,差异具有统计学意义(P＜0.05);72 h三七皂苷组NO含量、NOS活力较同时段模型组明显降低(P＜0.05,P＜0.01).而三七复方组和正常对照组比较差异无统计学意义(P＞0.05).结论三七复方、三七氨...

Objective To evaluate the effect of active principle of panax notoginseng on change of vitality in culture fluid of NO and NOS from human endometrial cell infammatory model. Methods The cell model of inflammatory human endometium was induced by active prineiple of panax notnginseng, which was interposed by the best concentration established in former experiment. And vitaility of NO, NOS has been determinated in 48 h and 72 h. Result The active prineiple of panax notoginseng can distinctly decrease NO, NOS of the RPMI1640 of human endometrial cell to near normality. Condusion The compound of pa...