Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

She, Ruining;Liu, Danhong;Liao, Jun;Wang, Guozuo;Ge, Jinwen*;...

通讯作者：

Ge, Jinwen;Mei, ZG;Ge, JW

作者机构：

[She, Ruining; Ge, Jinwen; Mei, Zhigang; Wang, Guozuo] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Key Lab Hunan Prov Integrated Tradit Chinese & Wes, Changsha, Hunan, Peoples R China.

[Liu, Danhong; Liao, Jun] Hunan Univ Chinese Med, Med Sch, Changsha, Hunan, Peoples R China.

[Ge, Jinwen] Hunan Acad Tradit Chinese Med, Changsha, Hunan, Peoples R China.

[Mei, Zhigang] China Three Gorges Univ, Third Grade Pharmacol Lab Chinese Med Approved Sta, Yichang, Hubei, Peoples R China.

通讯机构：

[Ge, JW; Mei, ZG ; Ge, JW ] H

Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Key Lab Hunan Prov Integrated Tradit Chinese & Wes, Changsha, Hunan, Peoples R China.

Hunan Acad Tradit Chinese Med, Changsha, Hunan, Peoples R China.

China Three Gorges Univ, Third Grade Pharmacol Lab Chinese Med Approved Sta, Yichang, Hubei, Peoples R China.

语种：

英文

关键词：

ischemic stroke;cerebral ischemia/reperfusion injury (CI/RI);mitochondrial dysfunctions;PANoptosis;PANoptosome;ferroptosis

期刊：

Frontiers in Cellular Neuroscience

ISSN：

1662-5102

年：

2023

卷：

页码：

1191629

DOI：

10.3389/fncel.2023.1191629

基金类别：

This work was supported from the National Natural Science Foundation of China (82174167), the Key Project of Hunan Province Education Department (20A366), the Project of Natural Science Foundation of Hunan Province (2021JJ30499), and the Fund for Youth Top Talent Project of Hubei Provincial Health and Family Planning Commission (EWT-2019-48).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

中西医结合学院

摘要：

Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury (CI/RI) is a cascade of pathophysiological events following the restoration of blood flow and reoxygenation, which not only directly damages brain tissue, but also enhances a series of pathological signaling cascades, contributing to inflammation, further aggravate the damage of brain tissue. Paradoxically, there are still no effective methods to prevent CI/RI, since the detailed underlying mechanisms remain vague. M...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问