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The pathological effect of Helicobacter pylori infection on liver tissues in mice

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成果类型:
期刊论文
作者:
Huang, Y.;Tian, X. -F;Fan, X. -G.*;Fu, C. -Y.;Zhu, C.
通讯作者:
Fan, X. -G.
作者机构:
[Fan, X. -G.; Zhu, C.; Tian, X. -F; Huang, Y.] Cent S Univ, Xiangya Hosp, Dept Infect Dis, Changsha 410008, Hunan, Peoples R China.
[Fu, C. -Y.] Cent S Univ, Xiangya Sch Med, Dept Pathol, Changsha 410008, Hunan, Peoples R China.
[Tian, X. -F] Hunan Univ Tradit Chinese Med, Dept Integrat Med, Changsha, Hunan, Peoples R China.
通讯机构:
[Fan, X. -G.] C
Cent S Univ, Xiangya Hosp, Dept Infect Dis, Changsha 410008, Hunan, Peoples R China.
语种:
英文
关键词:
C57BL/6 mouse;Helicobacter pylori;hepatitis;hepatocellular;nested PCR
期刊:
Clinical Microbiology and Infection
ISSN:
1198-743X
年:
2009
卷:
15
期:
9
页码:
843-849
机构署名:
本校为其他机构
摘要:
Helicobacter pylori infection is associated with chronic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. Some reports also suggest that it causes extragastric disease, including hepatitis. In this study, the pathological changes in the liver and gall bladder in H. pylori-colonized C57BL/6 mice were investigated. Twenty mice were inoculated orally with H. pylori strain SS1, and ten controls were injected with phosphate-buffered saline. Gastric colonization with H. pylori was assessed at 2 months a...

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