期刊论文

中文

中国医师杂志

1008-1372

2019

21

11

1617-1620

10.3760/cma.j.issn.1008-1372.2019.11.005

(81603512):国家自然科学基金 (20180097,20180364,2019047):湖南省卫生计生委课题 (2017A04,2017B01):湖南省脑科医院院级课题 (81603512):National Natural Science Foundation of China (20180097,20180364,2019047):Health and Family Planning Commission of Hunan Province (2017A04,2017B01):Project of Brain Hospital of Hunan Province

本校为第一机构

目的探讨柴胡加龙骨牡蛎汤（CLMD）对颞叶癫痫患者脑电图及血清神经生长因子（NGF）、脑源性神经营养因子（BDNF）水平的影响。方法将138例颞叶癫痫患者,采用单盲随机对照实验设计,分为奥卡西平组67例、奥卡西平+CLMD组71例,治疗28 d后,观察两组脑电图变化、血清中NGF、BDNF变化等。结果奥卡西平+CLMD组脑电图有效率为81. 8%,明显高于奥卡西平组的50. 7%,差异有统计学意义（P

Objective To observe influences of Chaihu-Longgu-Muli decoction (CLMD) on electroencephalogram (EEG),serum nerve growth factor (NGF) and brain derived neurotrophie factor (BDNF) level of patients with temporal lobe epilepsy.Methods Single blind randomized controlled trial design was used.138 patients with temporal lobe epilepsy were divided into oxcarbazepine group (including 67 patients),oxcarbazepine + CLMD group (including 71 patients).After 28 d of treatment,EEG changes,NGF and BDNF changes in serum,and relevant serological indicator inspec...